causal inference

Regression and Causality

The causal effect of an intervention (treatment/exposure) on an outcome can be estimated by: i) specifying knowledge about the data-generating process; ii) assessing under what assumptions a target quantity, such as for example a causal odds ratio, can be identified given the specified knowledge (and given the measured data); and then, iii) using appropriate statistical estimation techniques to estimate the desired parameter of interest.

The impact of delayed switch to second-line antiretroviral therapy on mortality, depending on failure time definition and CD4 count at failure

Increased Mortality with Delayed and Missed Switch to Second-Line Antiretroviral Therapy in South Africa

Regarding: Effect Estimates in Randomized Trials and Observational Studies: Comparing Apples with Apples

When and when not to use optimal model averaging

Using Longitudinal Targeted Maximum Likelihood Estimation in Complex Settings with Dynamic Interventions

Paradoxical Collider Effect in the Analysis of Non-Communicable Disease Epidemiological Data: a reproducible illustration and web application

What Should We Do When HIV-positive Children Fail First-line Combination Antiretroviral Therapy? A Comparison of 4 ART Management Strategies

Effect Modification and Collapsibility in Evaluations of Public Health Interventions

The Effect of Electrical Load Shedding on Pediatric Hospital Admissions in South Africa

The Republic of South Africa (SA) faced repeated episodes of temporary power shutdowns in 2014/2015, but also in the years thereafter. Based on my co-author’s experience at the burns unit at Red Cross children’s hospital, we had the hypothesis that this may have caused an increase in pediatric hospital admissions.